Devon Partnership NHS Trust was caring for zero coronavirus patients in hospital as of Wednesday, figures show.
NHS England data shows no people were being treated in hospital for Covid-19 at 8am on November 9.
There were four beds occupied by Covid-19 patients four weeks ago in Devon Partnership NHS Trust.
Across England there were 5,010 people in hospital with Covid as of November 16, with 122 of them in mechanical ventilation beds.
The number of Covid-19 patients hospitalised nationally has decreased by 52% in the last four weeks, while the number on mechanical ventilators has decreased by 41%.
The figures also show that no new Covid patients were admitted to hospital in Devon Partnership NHS Trust in the week to November 14.